Frank M Sacks Selected Research

Apolipoprotein C-III

12/2021	Changes in gut-microbiota-related metabolites and long-term improvements in lipoprotein subspecies in overweight and obese adults: the POUNDS lost trial.
1/2021	HDL Containing Apolipoprotein C-III is Associated with Insulin Sensitivity: A Multicenter Cohort Study.
1/2021	ApoC-III is a novel inducer of calcification in human aortic valves.
1/2019	Apolipoprotein C-III and its defined lipoprotein subspecies in relation to incident diabetes: the Multi-Ethnic Study of Atherosclerosis.
1/2018	High-Density Lipoprotein Subspecies Defined by Presence of Apolipoprotein C-III and Incident Coronary Heart Disease in Four Cohorts.
1/2018	High density lipoprotein with apolipoprotein C-III is associated with carotid intima-media thickness among generally healthy individuals.
9/2017	Apolipoprotein C-III and High-Density Lipoprotein Subspecies Defined by Apolipoprotein C-III in Relation to Diabetes Risk.
11/2016	The effect of omega-3 carboxylic acids on apolipoprotein CIII-containing lipoproteins in severe hypertriglyceridemia.
7/2015	The risk of cardiovascular events with increased apolipoprotein CIII: A systematic review and meta-analysis.
2/2015	The crucial roles of apolipoproteins E and C-III in apoB lipoprotein metabolism in normolipidemia and hypertriglyceridemia.

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Frank M Sacks Research Topics

Disease

43	Coronary Disease (Coronary Heart Disease) 08/2022 - 03/2002
41	Overweight 01/2022 - 02/2009
37	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 12/2002
34	Weight Loss (Weight Reduction) 01/2022 - 02/2006
29	Insulin Resistance 01/2022 - 01/2005
18	Obesity 01/2022 - 11/2008
16	Atherosclerosis 01/2022 - 11/2005
14	Body Weight (Weight, Body) 01/2022 - 02/2009
14	Myocardial Infarction 01/2014 - 01/2003
11	Hypertension (High Blood Pressure) 11/2017 - 11/2002
9	Inflammation (Inflammations) 01/2022 - 02/2006
8	Dyslipidemias (Dyslipidemia) 01/2022 - 04/2003
8	Type 2 Diabetes Mellitus (MODY) 11/2017 - 11/2008
8	Hypertriglyceridemia 11/2016 - 04/2003
7	Genetic Risk Score 12/2020 - 07/2016
7	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2013 - 02/2006
6	Coronary Artery Disease (Coronary Atherosclerosis) 02/2014 - 03/2004
5	Heart Diseases (Heart Disease) 01/2016 - 04/2009
4	Genetic Predisposition to Disease (Genetic Predisposition) 12/2020 - 09/2016
4	Stroke (Strokes) 03/2011 - 01/2003
4	Chronic Renal Insufficiency 07/2005 - 01/2003
3	Hyperlipidemias (Hyperlipidemia) 01/2022 - 12/2002
3	Cognitive Dysfunction 01/2021 - 09/2015
3	Vascular Diseases (Vascular Disease) 11/2015 - 02/2013
3	Atrial Fibrillation 06/2014 - 03/2012
3	Diabetes Mellitus 03/2014 - 07/2003
3	Heart Failure 08/2012 - 08/2011
3	Acute Coronary Syndrome 01/2011 - 07/2005
2	Neoplasms (Cancer) 09/2017 - 05/2002
2	Abdominal Obesity 11/2016 - 08/2015
2	Isolated Systolic Hypertension 09/2015 - 02/2006
2	Diabetic Nephropathies (Diabetic Nephropathy) 03/2014 - 12/2008
2	Kidney Diseases (Kidney Disease) 03/2014 - 06/2003
1	Prostatic Neoplasms (Prostate Cancer) 08/2022

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 08/2022 - 11/2005
24	Apolipoprotein C-IIIIBA 12/2021 - 04/2003
23	Triglycerides (Triacylglycerol)IBA 10/2020 - 03/2002
19	CarbohydratesIBA 01/2022 - 12/2002
19	HDL CholesterolIBA 11/2019 - 03/2002
18	Lipoproteins (Lipoprotein)IBA 12/2021 - 12/2002
18	Pravastatin (Pravachol)FDA LinkGeneric 07/2014 - 03/2002
16	CholesterolIBA 08/2022 - 01/2003
16	Insulin (Novolin)FDA Link 02/2021 - 08/2011
15	oxidized low density lipoproteinIBA 01/2022 - 03/2002
15	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 02/2012
15	ApolipoproteinsIBA 01/2022 - 07/2003
15	LDL CholesterolIBA 07/2017 - 03/2002
15	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 07/2014 - 01/2003
13	Dietary Fats (Dietary Fat)IBA 01/2022 - 12/2002
12	HDL LipoproteinsIBA 01/2022 - 07/2002
12	LipidsIBA 01/2018 - 05/2003
11	Apolipoproteins B (ApoB)IBA 08/2022 - 04/2003
10	LDL Lipoproteins (beta Lipoproteins)IBA 01/2021 - 07/2003
8	SodiumIBA 01/2022 - 07/2004
8	Unsaturated FatsIBA 01/2020 - 11/2005
6	Apolipoproteins E (ApoE)IBA 01/2022 - 04/2010
5	Lipoprotein(a)IBA 01/2021 - 08/2004
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 08/2012
5	Amino Acids FDA Link 01/2019 - 11/2005
5	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2019 - 01/2016
4	trimethyloxamine (trimethylamine N-oxide)IBA 12/2021 - 01/2018
4	Dietary ProteinsIBA 12/2019 - 05/2014
4	Dietary Carbohydrates (Carbohydrate, Dietary)IBA 01/2016 - 12/2014
4	Fatty Acids (Saturated Fatty Acids)IBA 06/2014 - 08/2011
3	Cholesterol Ester Transfer ProteinsIBA 01/2022 - 03/2004
3	FatsIBA 01/2022 - 12/2002
3	Carnitine (L-Carnitine)FDA LinkGeneric 12/2021 - 01/2018
3	C-Reactive ProteinIBA 01/2021 - 04/2013
3	VLDL LipoproteinsIBA 01/2021 - 04/2010
3	Dietary Fiber FDA Link 01/2021 - 03/2019
3	Pharmaceutical PreparationsIBA 09/2016 - 12/2002
3	Phospholipids (Phosphatides)FDA LinkGeneric 06/2014 - 03/2012
2	Atorvastatin (Lipitor)FDA Link 01/2022 - 10/2005
2	SaltsIBA 12/2021 - 02/2006
2	Plant Oils (Vegetable Oils)IBA 12/2021 - 01/2013
2	Amylases FDA Link 01/2020 - 01/2017
2	Choline (Choline Chloride)IBA 01/2019 - 01/2018
2	Vitamin D FDA LinkGeneric 11/2018 - 12/2015
2	Antihypertensive Agents (Antihypertensives)IBA 11/2017 - 07/2006
2	Branched-Chain Amino AcidsIBA 02/2016 - 03/2013
2	Aromatic Amino Acids (Aromatic Amino Acid)IBA 02/2016 - 03/2013
2	Peptides (Polypeptides)IBA 08/2015 - 02/2012
2	Neuropeptide YIBA 08/2015 - 11/2012
2	low density lipoprotein inhibitorIBA 07/2015 - 04/2010
2	BMS201038IBA 09/2014 - 03/2014
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2013 - 08/2012
2	alpha-Linolenic Acid (Linolenic Acid)IBA 01/2013 - 08/2012
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 03/2012 - 02/2006
2	Fenofibrate (CiL)FDA LinkGeneric 12/2008 - 12/2008
2	NF-kappa B (NF-kB)IBA 01/2007 - 08/2006
2	CreatinineIBA 09/2004 - 01/2003

Therapy/Procedure

27	Reducing Diet 01/2022 - 08/2011
11	Therapeutics 01/2021 - 12/2002
9	Fat-Restricted Diet (Diet, Fat Restricted) 12/2020 - 08/2011
8	Dietary Approaches To Stop Hypertension 01/2021 - 11/2002
7	High-Protein Diet 01/2022 - 11/2012
3	Caloric Restriction 10/2019 - 01/2017
2	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 10/2018 - 12/2014
2	Secondary Prevention 01/2004 - 01/2003
1	Prostatectomy (Retropubic Prostatectomy) 08/2022